Article

Assessing the contribution of genes involved in monogenic bone disorders to the etiology of atypical femoral fractures

2024-06-05

Abstract excerpt

<title>Abstract</title> <p>Background Recent studies suggested that genetic variants associated with monogenic bone disorders were involved in the pathogenesis of atypical femoral fractures (AFF). Here, we aim to identify rare genetic variants by whole exome sequencing in genes involved in monogenic rare skeletal diseases in 12 women with AFF and 4 controls without any fracture. Results Out of 33 genetic varian...

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Literature Corpus work: 7c864d50-00ca-5816-9c00-7bf8dff1b5dc
DOI: 10.21203/rs.3.rs-4467437/v1

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