Article
The importance of the Wnt/β-catenin pathway and LRP5 protein in bone metabolism of postmenopausal women.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Feb 2019
Kamiński Adam, Karasiewicz Monika, Bogacz Anna, Dziekan Karolina, Seremak-Mrozikiewicz Agnieszka, Czerny Bogusław
Abstract excerpt
BACKGROUND: Postmenopausal osteoporosis is the most common metabolic bone disease among women. The Wnt signaling pathway has been known to be the critical regulator of osteoblastogenesis. Alterations in this mechanism may have consequences for bone remodeling in humans. OBJECTIVES: The aim of the study was to evaluate the frequency of genotypes and alleles of single nucleotide polymorphism (SNP) rs4988321 and...
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