Article
Identification of Haplotype Tag Single-Nucleotide Polymorphisms within the PPAR Family Genes and Their Clinical Relevance in Patients with Major Trauma.
International journal of environmental research and public health - 26 Mar 2016
Gao Jun-Wei, Zeng Ling, Zhang An-Qiang, Wang Xiao, Pan Wei, Du Ding-Yuan, Zhang Lian-Yang, Gu Wei, Jiang Jian-Xin
Abstract excerpt
BACKGROUND: Peroxisome proliferator-activated receptors (PPARs) play important roles in the development of inflammatory diseases and sepsis. Recently, genetic variants of PPARs genes have been widely studied in some inflammatory diseases. However, the association between PPAR family of genes polymorphisms and sepsis risk in trauma patients was little known. METHODS: SNPs were selected from the PPARs genes through...
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