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Article

A common haplotype of the LBP gene predisposes to severe sepsis.

Critical care medicine - 1 Oct 2009

Flores Carlos, Pérez-Méndez Lina, Maca-Meyer Nicole, Muriel Arturo, Espinosa Elena, Blanco Jesús, Sangüesa Rubén, Muros Mercedes, Garcia Joe G N, Villar Jesús

Abstract excerpt

OBJECTIVE: To investigate whether common variants across the LBP gene contribute to the development of severe sepsis. Sepsis is the leading cause of multiple system organ dysfunction and death in critically ill patients. The lipopolysaccharide-binding protein is an acute-phase protein that plays a dominant role in the genesis of sepsis by initiating signal transduction pathways leading to the activation of the...

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Identifiers

PMID: 19707138
DOI: 10.1097/CCM.0b013e3181a57b90

Genes

LBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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