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Article

Epithelial cells activate plasmacytoid dendritic cells improving their anti-HIV activity.

PloS one - 1 Jan 2011

Rodriguez Rodrigues Christian, Cabrini Mercedes, Remes Lenicov Federico, Sabatté Juan, Ceballos Ana, Jancic Carolina, Raiden Silvina, Ostrowski Matías, Silberstein Claudia, Geffner Jorge

Abstract excerpt

Plasmacytoid dendritic cells (pDCs) play a major role in anti-viral immunity by virtue of their ability to produce high amounts of type I interferons (IFNs) and a variety of inflammatory cytokines and chemokines in response to viral infections. Since recent studies have established that pDCs accumulate at the site of virus entry in the mucosa, here we analyzed whether epithelial cells were able to modulate the...

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Identifiers

PMID: 22163327
DOI: 10.1371/journal.pone.0028709
PMCID: PMC3233592

Genes

TLR7
TLR9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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