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Article

Human intestinal lamina propria CD1c+ dendritic cells display an activated phenotype at steady state and produce IL-23 in response to TLR7/8 stimulation.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2010

Dillon Stephanie M, Rogers Lisa M, Howe Rawleigh, Hostetler Lydia A, Buhrman Jonathan, McCarter Martin D, Wilson Cara C

Abstract excerpt

Intestinal dendritic cells (DCs) play key roles in mediating tolerance to commensal flora and inflammatory responses against mucosal pathogens. The mechanisms by which intestinal "conditioning" influences human DC responses to microbial stimuli remain poorly understood. Infections with viruses, s...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20483758
DOI: 10.4049/jimmunol.1000041

Genes

TLR7
TLR4
CCR7
TLR2
TLR5
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20483758-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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