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Article

Activation and selective IL-17 response of human Vγ9Vδ2 T lymphocytes by TLR-activated plasmacytoid dendritic cells.

Oncotarget - 20 Sept 2016

Lo Presti Elena, Caccamo Nadia, Orlando Valentina, Dieli Francesco, Meraviglia Serena

Abstract excerpt

Vγ9Vδ2 T cells and plasmacytoid dendritic cells (pDCs) are two distinct cell types of innate immunity that participate in early phases of immune response. We investigated whether a close functional relationship exists between these two cell populations using an in vitro co-culture in a human system.pDCs that had been activated by IL-3 and the TLR9 ligand CpG induced substantial activation of Vγ9Vδ2 T cells upon...

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Identifiers

PMID: 27590513
DOI: 10.18632/oncotarget.11755
PMCID: PMC5308624

Genes

ICOS
TLR9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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