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Article

Mutations in RNA Splicing Machinery in Human Cancers

12 Dec 2011

Abstract excerpt

Massively parallel sequencing of cancer genomes is revealing a panoramic view of the genetic drivers of human neoplasms. In this issue of the Journal, Wang et al.1 describe an analysis of the coding sequences of samples from 91 patients with chronic lymphocytic leukemia. The disease is characterized by the accumulation of mature B lymphocytes, and its genetic basis is being rapidly elucidated.2,3 Wang et al....

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PMID: 22150007
DOI: 10.1056/nejme1111584

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