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Article

SnapShot: Splicing Alterations in Cancer.

Cell - 9 Jan 2020

Rahman Mohammad Alinoor, Krainer Adrian R, Abdel-Wahab Omar

Abstract excerpt

RNA splicing, the spliceosome-catalyzed process by which pre-messenger RNA (pre-mRNA) is processed to mature mRNA, is altered in a number of ways in cancer. Tumor-specific splicing alterations are created by mutations that disrupt splicing-regulatory elements within genes and impair splicing recognition or by altering the RNA-binding preferences of individual splicing factors. This SnapShot summarizes our current...

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Identifiers

PMID: 31951519
DOI: 10.1016/j.cell.2019.12.011
PMCID: PMC7291876

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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