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Article

Pre-mRNA splicing aberrations and cancer.

Frontiers in bioscience : a journal and virtual library - 1 Jan 2008

Pettigrew Christopher A, Brown Melissa A

Abstract excerpt

Splicing requires the accurate recognition of exonic sequences from the surrounding thousands of nucleotides of intronic sequence and is achieved by the coordinate interplay of splicing regulatory elements in genes and the trans-acting RNA and protein molecules to which they bind. Infidelity in this process can have dramatic consequences for protein production, with an errors resulting in mRNA instability or the...

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Identifiers

PMID: 17981615
DOI: 10.2741/2747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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