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Article

RNA Splicing and Cancer.

Trends in cancer - 1 Aug 2020

Wang Eric, Aifantis Iannis

Abstract excerpt

RNA splicing is an essential process that governs many aspects of cellular proliferation, survival, and differentiation. Considering the importance of RNA splicing in gene regulation, alterations in this pathway have been implicated in many human cancers. Large-scale genomic studies have uncovered a spectrum of splicing machinery mutations that contribute to tumorigenesis. Moreover, cancer cells are capable of...

Topics

Antigens, Neoplasm
Antineoplastic Agents
Carcinogenesis
Gene Expression Regulation, Neoplastic
Humans
Immunotherapy
Mutation
Neoplasms
Protein Isoforms
RNA Splicing
RNA Splicing Factors
Sequence Analysis, RNA

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PMID: 32434734
DOI: 10.1016/j.trecan.2020.04.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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