Article
Relationship between FKBP5 polymorphisms and depression symptoms among kidney transplant recipients.
Depression and anxiety - 21 Dec 2011
Shinozaki Gen, Jowsey Sheila, Amer Hatem, Biernacka Joanna, Colby Colin, Walker Denise, Black John, Rundell James, Stegall Mark, Mrazek David A
Abstract excerpt
BACKGROUND: Several polymorphisms in FK506 Binding Protein gene (FKBP5) and a history of child abuse have been shown to be associated with an increased risk for posttraumatic stress disorder (PTSD). It has also been demonstrated that the same polymorphisms of FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. However, there are only limited...
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