Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Testing a diathesis-stress model: potential genetic risk factors for development of distress in context of acute leukemia diagnosis and transplant.

Psychosomatics - 1 Jan 2000

Romanowicz Magdalena, Ehlers Shawna, Walker Denise, Decker Paul, Rundell James, Shinozaki Gen, Litzow Mark, Hogan William, Mrazek David, Black John L

Abstract excerpt

OBJECTIVE: Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that has antidepressant-like effects in animals and may be implicated in the etiology of mood-related phenotypes, specifically in the context of stressful life events. We hypothesized that this single-nucleotide polymorp...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain-Derived Neurotrophic Factor
Share to CRF Receptor, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depression

Share to Leukemia

Share to Receptors, Corticotropin-Releasing Hormone

Share to Serotonin Plasma Membrane Transport Proteins

Share to Stress, Psychological

Share to Tacrolimus Binding Proteins

Source

Identifiers

PMID: 22652301
DOI: 10.1016/j.psym.2012.01.004

Genes

BDNF
CRHR1
FKBP5
TAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22652301-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Testing a diathesis-stress model: potential genetic risk factors for development of distress in context of acute leukemia diagnosis and transplant.PMID 22652301Read ↗

Interaction between early-life stress and FKBP5 gene variants in major depressive disorder and post-traumatic stress disorder: A systematic review and meta-analysis.Semantic proximity Read ↗

The BDNF Val66Met polymorphism: relation to familiar risk of affective disorder, BDNF levels and salivary cortisol.Semantic proximity Read ↗

Brain-derived neurotrophic factor (BDNF) Val66Met and adulthood chronic stress interact to affect depressive symptoms.Semantic proximity Read ↗

Relationship between FKBP5 polymorphisms and depression symptoms among kidney transplant recipients.Semantic proximity Read ↗

FKBP5 and CRHR1 polymorphisms moderate the stress-physical health association in a national sample.Semantic proximity Read ↗

FKBP5 genotype-dependent DNA methylation and mRNA regulation after psychosocial stress in remitted depression and healthy controls.Semantic proximity Read ↗

BDNF function as a potential mediator of bipolar disorder and post-traumatic stress disorder comorbiditySemantic proximity Read ↗

Brain-derived neurotrophic factor val66met genotype and early life stress effects upon bipolar course.Semantic proximity Read ↗

Unfavorable transcriptome profiles and social disadvantage in hematopoietic cell transplantation: a CIBMTR analysisSemantic proximity Read ↗

FoxO1, A2M, and TGF-β1: three novel genes predicting depression in gene X environment interactions are identified using cross-species and cross-tissues transcriptomic and miRNomic analyses.Semantic proximity Read ↗

Variations in FKBP5 and BDNF genes are suggestively associated with depression in a Swedish population-based cohort.Semantic proximity Read ↗

Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.