Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults.

JAMA - 19 Mar 2008

Binder Elisabeth B, Bradley Rebekah G, Liu Wei, Epstein Michael P, Deveau Todd C, Mercer Kristina B, Tang Yilang, Gillespie Charles F, Heim Christine M, Nemeroff Charles B, Schwartz Ann C, Cubells Joseph F, Ressler Kerry J

Abstract excerpt

CONTEXT: In addition to trauma exposure, other factors contribute to risk for development of posttraumatic stress disorder (PTSD) in adulthood. Both genetic and environmental factors are contributory, with child abuse providing significant risk liability. OBJECTIVE: To increase understanding of genetic and environmental risk factors as well as their interaction in the development of PTSD by gene x environment...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child Abuse
Share to Dexamethasone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrocortisone

Share to Poverty

Share to Receptors, Glucocorticoid

Share to Stress Disorders, Post-Traumatic

Share to Tacrolimus Binding Proteins

Share to Urban Population

Source

Open in PubMed Open full text

Identifiers

PMID: 18349090
DOI: 10.1001/jama.299.11.1291
PMCID: PMC2441757

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults.PMID 18349090Read ↗

Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder.Semantic proximity Read ↗

FKBP5 polymorphisms, childhood abuse, and PTSD symptoms: Results from the National Health and Resilience in Veterans Study.Semantic proximity Read ↗

The effects of early trauma and the FKBP5 gene on PTSD and the HPA axis in a clinical sample of Gulf War veterans.Semantic proximity Read ↗

Maternal posttraumatic stress and FKBP5 Genotype interact to predict trauma-related symptoms in preschool-age offspring.Semantic proximity Read ↗

Moderation of adult depression by a polymorphism in the FKBP5 gene and childhood physical abuse in the general population.Semantic proximity Read ↗

Attachment style moderates effects of FKBP5 polymorphisms and childhood abuse on post-traumatic stress symptoms: Results from the National Health and Resilience in Veterans Study.Semantic proximity Read ↗

Interaction of FKBP5, a stress-related gene, with childhood trauma increases the risk for attempting suicide.Semantic proximity Read ↗

FKBP5 and CRHR1 polymorphisms moderate the stress-physical health association in a national sample.Semantic proximity Read ↗

FKBP5 genotype interacts with early life trauma to predict heavy drinking in college students.Semantic proximity Read ↗

FKBP5 polymorphisms modify the effects of childhood trauma.Semantic proximity Read ↗

FKBP5 as a possible moderator of the psychosis-inducing effects of childhood trauma.Semantic proximity Read ↗

Interaction between early-life stress and FKBP5 gene variants in major depressive disorder and post-traumatic stress disorder: A systematic review and meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.