Article
Osteopontin alleles are associated with clinical characteristics in systemic lupus erythematosus.
Journal of biomedicine & biotechnology - 1 Jan 2011
Trivedi Tarak, Franek Beverly S, Green Stephanie L, Kariuki Silvia N, Kumabe Marissa, Mikolaitis Rachel A, Jolly Meenakshi, Utset Tammy O, Niewold Timothy B
Abstract excerpt
Variants of the osteopontin (OPN) gene have been associated with systemic lupus erythematosus (SLE) susceptibility and cytokine profiles in SLE patients. It is not known whether these alleles are associated with specific clinical phenotypes in SLE. We studied 252 well-characterized SLE patients from a multiethnic cohort, genotyping the rs11730582, rs28357094, rs6532040, and rs9138 SNPs in the OPN gene. Ancestry...
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