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Article

Association of the rs1126616 and rs9138 Variants in the SPP1 Gene among Mexican Patients with Systemic Lupus Erythematosus and Lupus Nephritis.

International journal of molecular sciences - 13 Jan 2024

Rivera-Cameras Alicia, Gallegos-Arreola Martha Patricia, Morán-Moguel María Cristina, Salazar-Páramo Mario, Alcaraz-López Miriam Fabiola, Echeverría-González Gustavo, Topete-Reyes Jorge Fernando, Franco-Chávez Sergio Adalberto, Dávalos-Rodríguez Ingrid Patricia

Abstract excerpt

Systemic lupus erythematosus (SLE) is a multisystem disease considered a prototype of the main autoimmune disease and presents serious complications, such as lupus nephritis (LN), which generates a significant impact on morbidity and mortality. The SPP1 gene encodes the osteopontin (OPN) protein, which plays a crucial role in the regulation of inflammation and immunity. The variants rs1126616 and rs9138 of this...

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Identifiers

PMID: 38256074
DOI: 10.3390/ijms25021000
PMCID: PMC10816335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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