Article
Associations Between Osteopontin Variants and Systemic Lupus Erythematosus: A Meta-Analysis.
Genetic testing and molecular biomarkers - 1 Sept 2023
Lee Young Ho, Song Gwan Gyu
Abstract excerpt
Objective: Osteopontin (OPN) increases T-cell proliferation, interferon production, and CD40 ligand expression, which leads to B-cell proliferation and antibody production. This study was designed to determine whether OPN variants are associated with susceptibility to systemic lupus erythematosus [SLE]. Methods: We searched the Medline, Embase, and KoreaMed databases for available articles. We performed a...
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