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Article

Association analysis of PON2 genetic variants with serum paraoxonase activity and systemic lupus erythematosus.

BMC medical genetics - 11 Jan 2011

Dasgupta Sudeshna, Demirci F Yesim, Dressen Amy S, Kao Amy H, Rhew Elisa Y, Ramsey-Goldman Rosalind, Manzi Susan, Kammerer Candace M, Kamboh M Ilyas

Abstract excerpt

BACKGROUND: Low serum paraoxonase (PON) activity is associated with the risk of coronary artery disease, diabetes and systemic lupus erythematosus (SLE). Our prior studies have shown that the PON1/rs662 (p.Gln192Arg), PON1/rs854560 (p.Leu55Met), PON3/rs17884563 and PON3/ SNPs (single nucleotide polymorphisms) significantly affect serum PON activity. Since PON1, PON2 and PON3 share high degree of...

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Source

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Identifiers

PMID: 21223581
DOI: 10.1186/1471-2350-12-7
PMCID: PMC3030528

Genes

PON2
PON1
PON3

Variants

rs662
rs854560
rs6954345

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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