Article
Clinical and genetic risk factors for pneumonia in systemic lupus erythematosus.
Arthritis and rheumatism - 1 Aug 2007
Kinder Brent W, Freemer Michelle M, King Talmadge E, Lum Raymond F, Nititham Joanne, Taylor Kim, Edberg Jeffrey C, Bridges S Louis, Criswell Lindsey A
Abstract excerpt
OBJECTIVE: To define the contribution of polymorphisms in genes encoding tumor necrosis factor (TNF), mannose-binding lectin (MBL), and Fcgamma receptor IIa (FCGR2A) as well as clinical factors, to the development of pneumonia in patients with systemic lupus erythematosus (SLE). METHODS: We studied 282 SLE patients from a multiethnic cohort. Pneumonia events and clinical risk factors for pneumonia were identified...
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