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Article

Genetic variants in interferon regulatory factor 2 (IRF2) are associated with atopic dermatitis and eczema herpeticum.

The Journal of investigative dermatology - 1 Mar 2012

Gao Pei-Song, Leung Donald Y M, Rafaels Nicholas M, Boguniewicz Mark, Hand Tracey, Gao Li, Hata Tissa R, Schneider Lynda C, Hanifin Jon M, Beaty Terri H, Beck Lisa A, Weinberg Adriana, Barnes Kathleen C

Abstract excerpt

Interferon regulatory factor 2 (IRF2) is a member of a family of transcriptional factors involved in the modulation of IFN-induced immune responses to viral infection. To test whether genetic variants in IRF2 predict risk of atopic dermatitis (AD) and ADEH (atopic dermatitis complicated by eczema herpeticum), we genotyped 78 IRF2 tagging single-nucleotide polymorphisms (SNPs) in both European-American (n = 435)...

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Identifiers

PMID: 22113474
DOI: 10.1038/jid.2011.374
PMCID: PMC3278591

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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