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Article

Mutation and association analysis of the interferon regulatory factor 2 gene (IRF2) with atopic dermatitis.

Journal of human genetics - 1 Jan 2001

Nishio Y, Noguchi E, Ito S, Ichikawa E, Umebayashi Y, Otsuka F, Arinami T

Abstract excerpt

Interferon regulatory factor 2 (IRF-2) is a member of a family of transcriptional factors involved in the modulation of cellular responses to interferons (IFNs) and viral infection as well as in the regulation of cell growth and transformation. Irf2 knockout mice show T helper 1 (Th1) cell development defect and spontaneous development of an inflammatory skin disease. To determine if there are any mutations in...

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Identifiers

PMID: 11721886
DOI: 10.1007/s100380170018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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