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Article

IRF-1 gene variations influence IgE regulation and atopy.

American journal of respiratory and critical care medicine - 15 Mar 2008

Schedel Michaela, Pinto Leonardo A, Schaub Bianca, Rosenstiel Philip, Cherkasov Dmitry, Cameron Lisa, Klopp Norman, Illig Thomas, Vogelberg Christian, Weiland Stephan K, von Mutius Erika, Lohoff Michael, Kabesch Michael

Abstract excerpt

RATIONALE: The development of atopic diseases is characterized by skewed immune responses to common allergens. Only recently, interferons have been identified to play a crucial role in these mechanisms. OBJECTIVES: Because interferon regulatory factor (IRF)-1 is critical for interferon expression...

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Source

Identifiers

PMID: 18079498
DOI: 10.1164/rccm.200703-373OC

Genes

EGR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18079498-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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