Article
Atopic dermatitis complicated by eczema herpeticum is associated with HLA B7 and reduced interferon-γ-producing CD8+ T cells.
The British journal of dermatology - 1 Sept 2013
Mathias R A, Weinberg A, Boguniewicz M, Zaccaro D J, Armstrong B, Schneider L C, Hata T R, Hanifin J M, Beck L A, Barnes K C, Leung D Y M
Abstract excerpt
BACKGROUND: The increased susceptibility of patients with atopic dermatitis (AD) to disseminated viral skin infections such as eczema herpeticum (ADEH+) is poorly understood. OBJECTIVES: The primary goal of the current study was to determine whether ADEH+ subjects have identifiable defects in cell-mediated immunity that reduce their ability to control viral infections. MATERIALS AND METHODS: In this study, we...
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