Article
The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling.
Molecular and cellular biology - 1 Feb 2002
Hagel Margit, George Elizabeth L, Kim Ann, Tamimi Rulla, Opitz Sarah L, Turner Christopher E, Imamoto Akira, Thomas Sheila M
Abstract excerpt
The integrin family of cell adhesion receptors are important for a diverse set of biological responses during development. Although many integrins have been shown to engage a similar set of cytoplasmic effector proteins in vitro, the importance of these proteins in the biological events mediated by different integrin receptors and ligands is uncertain. We have examined the role of one of the best-characterized...
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