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Article

SNCA and MAPT genes: Independent and joint effects in Parkinson disease in the Italian population.

Parkinsonism & related disorders - 1 Mar 2012

Trotta Luca, Guella Ilaria, Soldà Giulia, Sironi Francesca, Tesei Silvana, Canesi Margherita, Pezzoli Gianni, Goldwurm Stefano, Duga Stefano, Asselta Rosanna

Abstract excerpt

BACKGROUND: Significant efforts have been focused on investigating the contribution of common variants to Parkinson disease (PD) risk. Several independent GWAS and metanalysis studies have shown a genome-wide significant association of single nucleotide polymorphisms (SNPs) in the α-synuclein (SNCA) and microtubule-associated protein tau (MAPT) regions. Here we investigated the role of SNCA and MAPT as PD...

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Source

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Identifiers

PMID: 22104010
DOI: 10.1016/j.parkreldis.2011.10.014
PMCID: PMC3314966

Genes

SNCA
MAPT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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