Article
SNCA variant associated with Parkinson disease and plasma alpha-synuclein level.
Archives of neurology - 1 Nov 2010
Mata Ignacio F, Shi Min, Agarwal Pinky, Chung Kathryn A, Edwards Karen L, Factor Stewart A, Galasko Douglas R, Ginghina Carmen, Griffith Alida, Higgins Donald S, Kay Denise M, Kim Hojoong, Leverenz James B, Quinn Joseph F, Roberts John W, Samii Ali, Snapinn Katherine W, Tsuang Debby W, Yearout Dora, Zhang Jing, Payami Haydeh, Zabetian Cyrus P
Abstract excerpt
BACKGROUND: A functional repeat polymorphism in the SNCA promoter (REP1) conveys susceptibility for Parkinson disease (PD). There is also increasing evidence that single-nucleotide polymorphisms (SNPs) elsewhere in the gene are associated with PD risk. OBJECTIVES: To further explore the associati...
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