Article
SNCA, MAPT, and GSK3B in Parkinson disease: a gene-gene interaction study.
European journal of neurology - 1 Jun 2011
Wider C, Vilariño-Güell C, Heckman M G, Jasinska-Myga B, Ortolaza-Soto A I, Diehl N N, Crook J E, Cobb S A, Bacon J A, Aasly J O, Gibson J M, Lynch T, Uitti R J, Wszolek Z K, Farrer M J, Ross O A
Abstract excerpt
BACKGROUND AND PURPOSE: Recent evidence suggests that variation in the SNCA, MAPT, and GSK3B genes interacts in affecting risk for Parkinson disease (PD). In the current study, we attempt to validate previously published findings, evaluating gene-gene interactions between SNCA, MAPT, and GSK3B in association with PD. METHODS: Three Caucasian PD patient-control series from the United States, Ireland, and Norway...
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