Article
Multiple regulatory roles of the carboxy terminus of Ste2p a yeast GPCR.
Pharmacological research - 1 Jan 2012
Kim Kyeong-Man, Lee Yong-Hun, Akal-Strader Ayca, Uddin M Seraj, Hauser Melinda, Naider Fred, Becker Jeffrey M
Abstract excerpt
Signaling and internalization of Ste2p, a model G protein-coupled receptor (GPCR) from the yeast Saccharomyces cerevisiae, are reported to be regulated by phosphorylation status of serine (S) and threonine (T) residues located in the cytoplasmic C-terminus. Although the functional roles of S/T residues located in certain C-terminus regions are relatively well characterized, systemic analyses have not been...
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