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Article

LCAT, HDL cholesterol and ischemic cardiovascular disease: a Mendelian randomization study of HDL cholesterol in 54,500 individuals.

The Journal of clinical endocrinology and metabolism - 1 Feb 2012

Haase Christiane L, Tybjærg-Hansen Anne, Qayyum Abbas Ali, Schou Jesper, Nordestgaard Børge G, Frikke-Schmidt Ruth

Abstract excerpt

BACKGROUND: Epidemiologically, high-density lipoprotein (HDL) cholesterol levels associate inversely with risk of ischemic cardiovascular disease. Whether this is a causal relation is unclear. METHODS: We studied 10,281 participants in the Copenhagen City Heart Study (CCHS) and 50,523 participants in the Copenhagen General Population Study (CGPS), of which 991 and 1,693 participants, respectively, had developed...

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Identifiers

PMID: 22090275
DOI: 10.1210/jc.2011-1846

Genes

LCAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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