Article
Independent Causal Effect of Remnant Cholesterol on Atherosclerotic Cardiovascular Outcomes: A Mendelian Randomization Study.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2023
Navarese Eliano P, Vine Donna, Proctor Spencer, Grzelakowska Klaudyna, Berti Sergio, Kubica Jacek, Raggi Paolo
Abstract excerpt
BACKGROUND: Observational studies suggested that residual risk of cardiovascular events after LDL (low-density lipoprotein) cholesterol lowering may be linked to remnant cholesterol (RC). We conducted a large-scale Mendelian randomization study to investigate the causal role of RC to predict coronary artery disease (CAD), myocardial infarction (MI), and stroke risk. METHODS: We extracted single-nucleotide...
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