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Article

Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study.

Journal of the National Cancer Institute - 16 Mar 2011

Benn Marianne, Tybjærg-Hansen Anne, Stender Stefan, Frikke-Schmidt Ruth, Nordestgaard Børge G

Abstract excerpt

BACKGROUND: Low plasma levels of low-density lipoprotein (LDL) cholesterol are associated with an increased risk of cancer, but whether this association is causal is unclear. METHODS: We studied 10 613 participants in the Copenhagen City Heart Study (CCHS) and 59 566 participants in the Copenhagen General Population Study, 6816 of whom had developed cancer by May 2009. Individuals were genotyped for PCSK9 R46L...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 8
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21285406
DOI: 10.1093/jnci/djr008

Genes

ABCG8
APOE
PCSK9

Variants

rs11591147
rs11591147
rs11591147
rs11591147

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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