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Article

High Density Lipoprotein pathway as a therapeutic target for coronary heart disease: individual participant meta-analysis in 28,597 individuals with 4197 coronary events

2020-03-06

Abstract excerpt

<h4>Importance</h4> Cholesterol content in high-density lipoprotein particles (HDL-C) is associated inversely with coronary heart disease (CHD), but findings from Mendelian randomization studies and randomized trials of HDL-C raising drugs have questioned whether this link is causal. However, these analyses do not exclude a causal role for specific HDL sub-fractions of different density, mobility, size and composi...

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Literature Corpus work
313a5d4f-92d4-5169-9ba6-0a5e1441fbb6
DOI
10.1101/2020.03.02.19010173
Open publication

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High Density Lipoprotein pathway as a therapeutic target for coronary heart disease: individual participant meta-analysis in 28,597 individuals with 4197 coronary eventsDOI 10.1101/2020.03.02.19010173
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