Article
Identification of tumorigenic cells in Kras(G12D)-induced lung adenocarcinoma.
Cancer research - 1 Dec 2011
Cho Huan-Chieh, Lai Chao-Yang, Shao Li-En, Yu John
Abstract excerpt
We established an inducible Kras(G12D)-driven lung adenocarcinoma in CCSP-rtTA/TetO-Cre/LSL-Kras(G12D) mice that enable pursuits of the cellular and molecular processes involved in Kras-induced tumorigenesis. To investigate the cellular origin of this cancer, we first report a strategy using fluo...
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