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Article

Clinical significance of core gene mutations during the course of genotype C chronic hepatitis B virus infection.

Hepato-gastroenterology - 1 Jan 2000

Lee Dong Ho, Gwak Geum-Youn, Min Byung-Hoon, Choi Moon Suk, Lee Joon Hyeok, Koh Kwang Cheol, Paik Seung Woon, Yoo Byung Chul

Abstract excerpt

BACKGROUND/AIMS: The aim of this study was to investigate the association of HBV core gene mutations with disease severity in HBV-infected patients. METHODOLOGY: We included 249 genotype C HBV infected patients: 39 asymptomatic carriers (AC), 68 with chronic hepatitis (CH), 75 with liver cirrhosis (LC), and 67 with HCC. HBV DNA was extracted from patient sera and the HBV core gene was analyzed by PCR and...

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Identifiers

PMID: 22086694
DOI: 10.5754/hge08631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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