Article
Association between the various mutations in viral core promoter region to different stages of hepatitis B, ranging of asymptomatic carrier state to hepatocellular carcinoma.
The American journal of gastroenterology - 1 Jan 2011
Yin Jianhua, Xie Jiaxin, Liu Shijian, Zhang Hongwei, Han Lei, Lu Wenying, Shen Qiuxia, Xu Guozhang, Dong Hongjun, Shen Jie, Zhang Jun, Han Jiankang, Wang Lin, Liu Yan, Wang Fan, Zhao Jun, Zhang Qian, Ni Wu, Wang Hongyang, Cao Guangwen
Abstract excerpt
OBJECTIVES: The objective of this study was to determine the association of 19 mutations with frequencies ≥ 10% in the core promoter region of hepatitis B virus (HBV) with chronic hepatitis B (CHB), liver cirrhosis, and hepatocellular carcinoma (HCC). METHODS: Eight hundred forty-six asymptomatic hepatitis B surface antigen carriers (ASCs), 235 CHB patients, 188 cirrhosis patients, and 190 HCC patients with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.