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Article

Variations in codons 84-101 in the core nucleotide sequence correlate with hepatocellular injury in chronic hepatitis B virus infection.

The Journal of clinical investigation - 1 Jan 1992

Ehata T, Omata M, Yokosuka O, Hosoda K, Ohto M

Abstract excerpt

Individuals with chronic hepatitis B virus (HBV) infection are generally divided into asymptomatic healthy carriers and patients with chronic liver disease. Several studies have suggested that the hepatitis B core antigen could be an immunological target of cytotoxic T lymphocytes (CTL). To investigate the possible pressure site from CTL, the entire core region of HBV DNA was sequenced in 30 subjects (10...

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Share to Amino Acid Sequence
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

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Share to Polymerase Chain Reaction

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Share to Sequence Homology, Nucleic Acid

Share to T-Lymphocytes, Cytotoxic

Source

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Identifiers

PMID: 1729279
DOI: 10.1172/JCI115581
PMCID: PMC442853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Variations in codons 84-101 in the core nucleotide sequence correlate with hepatocellular injury in chronic hepatitis B virus infection.PMID 1729279Read ↗

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[Mutation in core and pre-core amino acid sequences of hepatitis B virus correlate with fulminant and severe hepatitis].Semantic proximity Read ↗

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