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Article

Naturally occurring hepatitis B virus core gene mutations.

Hepatology (Baltimore, Md.) - 1 Jul 1995

Akarca U S, Lok A S

Abstract excerpt

Mutations in the hepatitis B virus (HBV) core gene may influence disease activity by altering immune recognition sites or level of virus replication. Sera from 69 Chinese patients with chronic HBV infection were analyzed by direct sequencing of polymerase chain reaction amplification of HBV DNA to determine the frequency and location of naturally occurring HBV core gene mutations. All but one patient had...

Topics

Adolescent
Adult
Asian People
Base Sequence
Child
China
Chronic Disease
Cohort Studies
Female
Hepatitis B
Hepatitis B e Antigens
Hepatitis B virus
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Molecular Probes

Molecular Sequence Data

Mutation

Source

Identifiers

PMID: 7601433

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7601433-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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