Article
Mutations within the HBc gene of the hepatitis B virus: a study on Iranian patients.
Clinical laboratory - 1 Jan 2014
Zare-Bidaki Mohammad, Ayoobi Fatemeh, Hassanshahi Gholamhossein, Arababadi Mohammad Kazemi, Mirzaei Tayebeh, Darehdori Ahmad Shebanizade, Kennedy Derek
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) is a serious risk factor for several severe liver diseases such as cirrhosis and hepatocellular carcinoma. HBV, like other viruses, uses several mechanisms to escape from specific immune responses including the use of mutations in the genome which lead to epitope variations. There are several immune responses, including T helper cells, cytotoxic T lymphocytes, and B cells,...
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