Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations between polymorphisms in DNA repair genes and TP53 mutations in non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Jul 2011

Cho Sukki, Kim Min Jung, Choi Yi Young, Yoo Seung Soo, Lee Won Kee, Lee Eun Jin, Jang Eun Jeong, Bae Eun Young, Jin Guang, Jeon Hyo-Sung, Lee Shin Yup, Cha Sung-Ick, Park Tae In, Kim Chang Ho, Park Jae Yong

Abstract excerpt

This study was conducted to identify genetic factors predisposing to TP53 mutations in patients with non-small cell lung cancer (NSCLC). A comprehensive panel of potentially functional single nucleotide polymorphisms (SNPs) in DNA repair genes was evaluated in relation to TP53 mutations. Thirty-seven SNPs in 28 DNA repair genes were genotyped by a sequenome mass spectrometry-based genotyping assay in 173 NSCLCs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to DNA Repair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Lung Neoplasms

Share to Multivariate Analysis

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 21129811
DOI: 10.1016/j.lungcan.2010.10.023

Genes

OGG1
XPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations between polymorphisms in DNA repair genes and TP53 mutations in non-small cell lung cancer.PMID 21129811Read ↗

Potentially functional polymorphisms in DNA repair genes and non-small-cell lung cancer survival: a pathway-based analysis.Semantic proximity Read ↗

Deep sequencing of the TP53 gene reveals a potential risk allele for non-small cell lung cancer and supports the negative prognostic value of TP53 variants.Semantic proximity Read ↗

Comprehensive analysis of DNA repair gene polymorphisms and survival in patients with early stage non-small-cell lung cancer.Semantic proximity Read ↗

Polymorphisms in apoptosis-related genes and TP53 mutations in non-small cell lung cancer.Semantic proximity Read ↗

TP53 Mutation Mapping in Advanced Non-Small Cell Lung Cancer: A Real-World Retrospective Cohort Study.Semantic proximity Read ↗

Association of genetic polymorphisms in DNA repair pathway genes with non-small cell lung cancer risk.Semantic proximity Read ↗

DNA Repair Gene Polymorphisms in Relation to Non-Small Cell Lung Cancer Survival.Semantic proximity Read ↗

The genetic variations in DNA repair genes ERCC2 and XRCC1 were associated with the overall survival of advanced non-small-cell lung cancer patients.Semantic proximity Read ↗

Molecular epidemiology of non-small cell lung cancer.Semantic proximity Read ↗

Common genetic variation in TP53 is associated with lung cancer risk and prognosis in African Americans and somatic mutations in lung tumors.Semantic proximity Read ↗

Polymorphisms in DNA repair and apoptosis-related genes and clinical outcomes of patients with non-small cell lung cancer treated with first-line paclitaxel-cisplatin chemotherapy.Semantic proximity Read ↗

The XRCC1 and TP53 gene polymorphisms are associated with advanced-stage disease and early distant metastasis at diagnosis in non-small cell lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.