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Article

Association study of TP53 polymorphisms with lung cancer in a Korean population.

Journal of human genetics - 1 Jan 2008

Jung Hae-Yun, Whang Young Mi, Sung Jae Sook, Shin Hyoung Doo, Park Byung Lae, Kim Jun Suk, Shin Sang Won, Seo Hee Yun, Seo Jae Hong, Kim Yeul Hong

Abstract excerpt

The tumor suppressor gene, TP53, is located on chromosome 17p13.1 and is critical for DNA repair, cell-cycle control, and apoptosis. TP53 also plays a crucial function in the tumorigenesis of lung cancer. Inactivation of TP53 via genetic alterations such as missense mutations is often associated with lung cancer. In this study, potential association of TP53 polymorphisms with the risk of lung cancer was examined...

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PMID: 18363031
DOI: 10.1007/s10038-008-0278-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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