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Article

Apoptosis gene polymorphisms, age, smoking and the risk of non-small cell lung cancer.

Carcinogenesis - 1 Nov 2008

Ter-Minassian Monica, Zhai Rihong, Asomaning Kofi, Su Li, Zhou Wei, Liu Geoffrey, Heist Rebecca Suk, Lynch Thomas J, Wain John C, Lin Xihong, De Vivo Immaculata, Christiani David C

Abstract excerpt

Apoptosis is important for targeting cancer cells for destruction. Various single-nucleotide polymorphisms (SNPs) in apoptotic genes have been associated with increased risks in lung cancer, particularly FAS -1377 G>A (rs2234767), FASLG -844 C>T (rs763110), IL1B +3954 C>T Phe105Phe (rs1143634) and BAT3 Ser625Pro (rs1052486). We studied the association of these SNPs with non-small cell lung cancer (NSCLC) in a...

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Identifiers

PMID: 18757527
DOI: 10.1093/carcin/bgn205
PMCID: PMC2577138

Genes

FASLG
FAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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