Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms at p53, p73, and MDM2 loci modulate the risk of tobacco associated leukoplakia and oral cancer.

Molecular carcinogenesis - 1 Sept 2009

Misra Chaitali, Majumder Mousumi, Bajaj Swati, Ghosh Saurabh, Roy Bidyut, Roychoudhury Susanta

Abstract excerpt

Polymorphisms at loci controlling cellular processes such as cell cycle, DNA repair, and apoptosis may modulate the risk of cancer. We examined the association of two linked polymorphisms (G4C14-A4T14) at p73 and one polymorphism (309G > T) at MDM2 promoter with the risk of leukoplakia and oral cancer. The p73 and MDM2 genotypes were determined in 197 leukoplakia patients, 310 oral cancer patients and in 348...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mouth Neoplasms
Share to Odds Ratio

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proto-Oncogene Proteins c-mdm2

Share to Smoking

Share to Tobacco, Smokeless

Share to Tumor Protein p73

Share to Tumor Suppressor Protein p53

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 19204927
DOI: 10.1002/mc.20523

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms at p53, p73, and MDM2 loci modulate the risk of tobacco associated leukoplakia and oral cancer.PMID 19204927Read ↗

Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

MDM2 SNP309, gene-gene interaction, and tumor susceptibility: an updated meta-analysis.Semantic proximity Read ↗

Risk assessment of p53 genotypes and haplotypes in tobacco-associated leukoplakia and oral cancer patients from eastern Idia.Semantic proximity Read ↗

Combined p53-related genetic variants together with HPV infection increase oral cancer risk.Semantic proximity Read ↗

The role of P53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma.Semantic proximity Read ↗

MDM2 and TP53 Polymorphisms as Predictive Markers for Head and Neck Cancer in Northeast Indian Population: Effect of Gene-Gene and Gene-Environment Interactions.Semantic proximity Read ↗

Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer.Semantic proximity Read ↗

Impact of MDM2 single nucleotide polymorphism on oral squamous cell carcinoma risk.Semantic proximity Read ↗

Alterations in p53 Influence hTERT, VEGF and MMPs Expression in Oral Cancer Patients.Semantic proximity Read ↗

Genetic polymorphisms of MDM2 and TP53 genes are associated with risk of nasopharyngeal carcinoma in a Chinese population.Semantic proximity Read ↗

Effects of MDM2 promoter polymorphisms and p53 codon 72 polymorphism on risk and age at onset of squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

Combined analysis of the association between p73 G4C14-to-A4T14 polymorphisms and cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.