Article
Genotypic distribution of single nucleotide polymorphisms in oral cancer: global scene.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Nov 2016
Multani Shaleen, Saranath Dhananjaya
Abstract excerpt
Globocan 2012 reports the global oral cancer incidence of 300,373 new oral cancer cases annually, contributing to 2.1 % of the world cancer burden. The major well-established risk factors for oral cancer include tobacco, betel/areca nut, alcohol and high-risk oncogenic human papilloma virus (HPV) 16/18. However, only 5-10 % of individuals with high-risk lifestyle develop oral cancer. Thus, genomic variants in...
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