Article
Association of p53 and MDM2 polymorphisms with risk of human papillomavirus (HPV)-related esophageal squamous cell carcinoma (ESCC).
Cancer epidemiology - 1 Oct 2013
Yang Ju, Liu Bo, Li Wen, Xiong Huihua, Qiu Hong, Fu Qiang, Chen Bei, Hu Guangyuan, Yuan Xianglin
Abstract excerpt
PURPOSE: Though polymorphisms of the tumor suppressor gene p53 have been extensively investigated in numerous tumors, particularly tumors associated with human papillomavirus (HPV) infection. However, the results remain controversial. Our previous study showed that HPV serostatus is not an independent risk factor for esophageal squamous cell carcinoma (ESCC) in nonsmokers and nondrinkers. Given the roles of p53...
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