Article
The sec and prl genes of Escherichia coli.
Journal of bioenergetics and biomembranes - 1 Jun 1990
Bieker K L, Phillips G J, Silhavy T J
Abstract excerpt
Two general approaches have been used to define genetically the genes that encode components of the cellular protein export machinery. One of these strategies identifies mutations that confer a conditional-lethal, pleiotropic export defect (sec, secretion). The other identifies dominant suppressors of signal sequence mutations (prl, protein localization). Subsequent characterization reveals that in at least three...
Topics
- Bacterial Proteins
- Escherichia coli
- Mutation
- Protein Sorting Signals
- Suppression, Genetic
