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Article

prl mutations in the Escherichia coli secG gene.

The Journal of biological chemistry - 14 Feb 1997

Bost S, Belin D

Abstract excerpt

SecG, an integral membrane component of the Escherichia coli preprotein translocase, contributes to the efficiency of the export process by undergoing cycles of topology inversion in the membrane, coupled with the insertion-deinsertion cycles of SecA. We have previously identified sec alleles of secG that cause a generalized secretion defect. In this study, by screening mutagenized secG libraries for suppressors...

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Identifiers

PMID: 9020118
DOI: 10.1074/jbc.272.7.4087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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prl mutations in the Escherichia coli secG gene.PMID 9020118Read ↗

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The sec and prl genes of Escherichia coli.Semantic proximity Read ↗

A new genetic selection identifies essential residues in SecG, a component of the Escherichia coli protein export machinery.Semantic proximity Read ↗

Isolation and analysis of dominant secA mutations in Escherichia coli.Semantic proximity Read ↗

Mutations in the Sec61p channel affecting signal sequence recognition and membrane protein topology.Semantic proximity Read ↗

The F286Y mutation of PrlA4 tempers the signal sequence suppressor phenotype by reducing the SecA binding affinity.Semantic proximity Read ↗

SecY variants that interfere with Escherichia coli protein export in the presence of normal secY.Semantic proximity Read ↗

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