Novel prlA alleles defective in supporting staphylokinase processing in Escherichia coli.

Abstract excerpt

A class of prlA (secY) alleles of Escherichia coli (prlA4-1 and prlA401) which specifically block the export of staphylokinase has been identified (T. Iino and T. Sako, J. Biol. Chem. 263:19077-19082, 1988; T. Sako and T. Iino, J. Bacteriol. 170:5389-5391, 1988). To determine more precisely the r...

Topics

• Alleles
• Bacterial Outer Membrane Proteins
• Bacterial Proteins
• Biological Transport
• Escherichia coli
• Escherichia coli Proteins
• Genetic Complementation Test
• Metalloendopeptidases
• Mutation
• Protein Processing, Post-Translational
• Protein Sorting Signals
• SEC Translocation Channels
• Structure-Activity Relationship