Article
Modeling the effects of prl mutations on the Escherichia coli SecY complex.
Journal of bacteriology - 1 Sept 2005
Smith Margaret A, Clemons William M, DeMars Cathrine J, Flower Ann M
Abstract excerpt
The apparatus responsible for translocation of proteins across bacterial membranes is the conserved SecY complex, consisting of SecY, SecE, and SecG. Prior genetic analysis provided insight into the mechanisms of protein export, as well as the interactions between the component proteins. In particular, the prl suppressor alleles of secE and secY, which allow export of secretory proteins with defective signal...
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