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Article

Modeling the effects of prl mutations on the Escherichia coli SecY complex.

Journal of bacteriology - 1 Sept 2005

Smith Margaret A, Clemons William M, DeMars Cathrine J, Flower Ann M

Abstract excerpt

The apparatus responsible for translocation of proteins across bacterial membranes is the conserved SecY complex, consisting of SecY, SecE, and SecG. Prior genetic analysis provided insight into the mechanisms of protein export, as well as the interactions between the component proteins. In particular, the prl suppressor alleles of secE and secY, which allow export of secretory proteins with defective signal...

Topics

Escherichia coli
Escherichia coli Proteins
Membrane Proteins
Mutation
SEC Translocation Channels
Suppression, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 16159779
DOI: 10.1128/JB.187.18.6454-6465.2005
PMCID: PMC1236629

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Modeling the effects of prl mutations on the Escherichia coli SecY complex.PMID 16159779Read ↗

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