Article
One of three transmembrane stretches is sufficient for the functioning of the SecE protein, a membrane component of the E. coli secretion machinery.
The EMBO journal - 1 Jul 1991
Schatz P J, Bieker K L, Ottemann K M, Silhavy T J, Beckwith J
Abstract excerpt
The E. coli secE (prlG) gene codes for an integral cytoplasmic membrane protein which is part of the cell's secretory machinery. A deletion of nearly the entire gene renders the cell dependent on the presence of a complementing secE+ plasmid, indicating that the SecE protein is essential for growth. Deletions which remove carboxy-terminal sequences or substantial amounts near the amino-terminus of SecE can still...
Topics
- Alleles
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Chromosome Deletion
- Cold Temperature
- DNA, Bacterial
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial