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Article

A new genetic selection identifies essential residues in SecG, a component of the Escherichia coli protein export machinery.

The EMBO journal - 15 Sept 1995

Bost S, Belin D

Abstract excerpt

The signal sequence of the murine serine protease inhibitor PAI-2 promotes alkaline phosphatase export to the E. coli periplasm. However, high level expression of this chimeric protein interferes with cell growth. Since most suppressors of this toxic phenotype map to secA and secY, growth arrest results from a defective interaction of the chimeric protein with the export machinery. We have characterized...

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Identifiers

PMID: 7556084
DOI: 10.1002/j.1460-2075.1995.tb00120.x
PMCID: PMC394532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A new genetic selection identifies essential residues in SecG, a component of the Escherichia coli protein export machinery.PMID 7556084Read ↗

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The sec and prl genes of Escherichia coli.Semantic proximity Read ↗

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